Lesley Fallowfield trained at Guy's Hospital London as a nurse before completing a degree in Experimental Psychology. Research for her DPhil in Psychophysics was done at the Universities of Sussex and Cambridge. Her primary research interests include:
Assessment of Patient Reported Outcomes (PROs)in clinical trials of cancer therapy.
Development and assessment of supportive interventions for symptoms and side-effects of cancer and its treatment.
Communication- development and evaluation of innovative training course and materials to assist health care professionals' communicating with patients, their families and with clinical colleages.
Professor Fallowfield has contributed numerous articles to medical journals and has written three textbooks on QoL and communication in health care.
Following on from the successful BRCA DIRECT trial, NHS England has provided funding to implement the BRCA DIRECT digital pathway in 10-20 centres in England over an 18 month period.
Examines whether a short (8 min) film about Gene Expression Profiling (GEP) tests used in breast cancer (Oncotype DX® or Prosigna) helps improve patients‘ knowledge.
A phase III trial of surgery versus active monitoring for Low Risk DCIS (LORIS), incorporating a two year feasibility study. The aim of the main trial is to determine whether women with newly diagnosed low risk DCIS can safely avoid surgery, without detriment to their psychological well-being and can those patients who do require surgery be identified by pathological and radiological criteria.
Evaluation of a series of workshops around the UK building on the previous workshops but incorporating new materials covering extra topics and scenarios.
Development and implementation of training program from Healthcare Professional on how best to communicate with paitents who have metastatic disease.
Torr B, Jones C, Kavanaugh G, Hamill M, Allen S, Choi S et al. (2024)BRCA-DIRECT digital pathway for diagnostic germline genetic testing within a UK breast oncology setting: a randomised, non-inferiority trial. British Journal of Cancer 131, 1506-1515. Find it online here
01/10/2024
Sharon F. McGee, Mark Clemons, Gregory Pond, Jean-Michel Caudrelier, Michelle Liu, Mashari Jemaan Alzahrani, ... Jean-Marc Bourque (2024) A Randomized Trial Comparing Concurrent versus Sequential Radiation and Endocrine Therapy in Early-Stage, Hormone-Responsive Breast Cancer. Current Oncology; 31 (8) 4531-4545 Find it online here
07/08/2024
Jenkins V, Habibi R, Hall V, Leonard P, Lawn A, Naik J,...Fallowfield L. (2024) Roll-out of an educational workshop to improve knowledge and self-confidence of healthcare professionals engaged in mainstreaming of breast cancer genetics. PLoS ONE 19(7): e0307301. Find it online here
19/07/2024
Fatima Cardoso, Shani Paluch-Shimon, Eva Schumacher-Wulf, Leonor Matos, Karen Gelmon, Matti S. Aapro, ... Eric P. Winer (2024). 6th and 7th International consensus guidelines for the management of advanced breast cancer (ABC guidelines 6 and 7). The Breast; 76: 1-66 Find it online here
18/06/2024
Treasure T, Macbeth F, Fallowfield L. (2024) A prospective multicentre cohort study of colorectal lung metastasectomy with a nested randomized controlled trial: the key points from the pulmonary metastasectomy in colorectal cancer study. European Journal of Cardiothoracic Surgery; 65 (6): ezae216. Find it online here
03/06/2024
Burstein H, DeMichele A, Fallowfield L, Somerfield M, & Henry NL. (2024). Endocrine and Targeted Therapy for Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2 - Negative Metastatic Breast Cancer - Capivasertib-Fulvestrant: ASCO Rapid Recommendation Update. Journal of Clinical Oncology; Volume 42: 1450-1455 Find it online here
02/04/2024
Dilley J, Gentry-Maharaj A, Ryan A, Burnell M, Manchanda R, Kalsi J, ... & Menon U. (2023). Ovarian cancer symptoms in pre-clinical invasive epithelial ovarian cancer-An exploratory analysis nested within the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). Gynecologic Oncology; 179: 123-130. Find it online here
18/11/2023
Macbeth F, Fallowfield L, Treasure E, Ahmad I, Zheng Y, & Treasure T. (2023). Removal or ablation of asymptomatic lung metastases should be reconsidered. BMJ; 383. Find it online here
09/11/2023
Wheelwright S, Matthews L, Jenkins V, May S, Rea D, Fairbrother P, Gaunt C, Young J, Pirrie S, Wallis M G, Fallowfield L, on behalf of the LORIS Trial Management Group (2023).
Recruiting women with ductal carcinoma in situ to a randomised controlled trial: lessons from the LORIS study. Trials; 24(1): 670. Find it online here
14/10/2023
Menon U, Gentry-Maharaj A, Burnell M, Ryan A, Singh N, Manchanda R, ... & Parmar M K. (2023). Tumour stage, treatment, and survival of women with high-grade serous tubo-ovarian cancer in UKCTOCS: an exploratory analysis of a randomised controlled trial. The Lancet Oncology; 24(9): 1018-1028. Find it online here
29/08/2023