Chief Investigator - Prof Dame Lesley Fallowfield
Co-Investigator - Prof Val Jenkins
Researcher - Lucy Matthews
Researcher - Rachel Starkings
Data Manager - Shirley May
Funder: BCRF
Sponsor: Sussex University
IMPARTER 4
This research study follows on from our successful IMPARTER project, which showed the usefulness of 2 patient information films about gene expression profiling (GEP) tests for breast cancer. The short 8 minute films improved understanding over standard written leaflets in 120 women aged 45-75 who did not have breast cancer. We were confident that these results provide sufficient evidence of efficacy to test the films in an intervention study with patients.Patients with early stage breast cancer, whose tumour has been sent off for either an Oncotype DX or a Prosigna gene expression profiling test are eligible to take part in IMPARTER 4.
Those who consent will complete 3 online questionnaires measuring anxiety/intolerance of uncertainty, and then are allocated to one of two groups.
Group A: standard GEP information (usual practice/leaflet)
Group B: standard GEP information + link to the relevant film oncotype DX® or prosigna®)
Before the GEP results consultation, participants are interviewed about their understanding of the GEP test and asked for comments on any other information they may have received.
Finally all participants complete 2 further online questionnaires, measuring anxiety and satisfaction.
Participating clinicians also complete 2 questionnaires, satisfaction with the consultation and intolerance of uncertainty.
Number of patients recruited: 251
Current Stage:
Analysis and Write Up
Poster
IMPARTER:4 IMproving PAtient undeRstanding of Gene Expression Profiling Test Results: Phase 4 posters/IMPARTER4PosterBench_to_Bedside.pdf Presented at Bench to Beside conference 2024