A 3-year study on Progression Free Survival (PFS). This study aims to contribute an empirically derived patient perspective about the use of progression-free survival as an appropriate endpoint in clinical trials of cancer therapy. PFS is the length of time after cancer treatment that a patient lives with the disease without tests showing that it is worsening. Although PFS is used in clinical trials as a means of testing how well a new treatment might work, a longer PFS does not necessarily mean that overall survival is improved. So if patients derive PFS benefits but overall live no longer and they suffer unacceptable side-effects from the treatment then this PFS may be of little value. This is an extremely important study that has generated much interest already.  

Data analysis continues and publications include:

2017 Fallowfield LJ, Catt SL, May SF, Matthews L, Shilling VM, Simcock R, Westwell S, Jenkins VA. Therapeutic aims of drugs offering only progression-free survival are misunderstood by patients, and oncologists may be overly optimistic about likely benefits. Supportive Care in Cancer 2017, 25:237-244

Poster presentations

The British Psychosocial Oncology Society (BPOS) Annual Conference 16-17 March 2017 PDF document of trial summary poster

ASCO Cancer Survivorship Symposium, 28th January 2017. PDF document of trial summary poster

ASCO Palliative Care Conference, 23-25 October 2014 PDF document of trial summary poster

 

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